Kardiologie

Prof. Dr. med Silber

CURRICULUM VITAE
Sigmund Silber, MD, PhD
Professor of Medicine
FESC, FACC, FAHA
Cardiologist

sigmund@silber.com
www.sigmund-silber.com

Cardiology Practice and Heart Center at the Isar, Munich, Germany

Date of birth: May11th 1949 in Passau, Bavaria, Germany
Citizenship: Germany
Family Status: Married since 1972, two children
PROFESSIONAL EXPERIENCE and ACADEMIC DEGREES:
1968 B.S.-equivalent (Abitur at Rupprecht-Gymnasium, Munich, Germany)
1968 - 1974 Medical School at the University of Munich (Ludwig-Maximilians-University, LMU)
1970 - 1974 Research Associate
Institute for Experimental Cardiovascular Pharmacology, University of Munich
1975 Thesis (MD), Dissertation, Institute for Experimental Cardiovascular Pharmacology, University of Munich, Topic: "Effects of Aescin on the Circulation of the Cat", Magna cum Laude
1974-1975
Internships
  • Internal Medicine: Stiftsklinik Augustinum, Munich
  • (Director: Prof. Dr. med. D. Michel)
  • Gynecology: II. Frauenklinik of the Univ. of Munich
  • (Director: Prof. Dr. med. K. Richter)
  • General Surgery: Krankenhaus Munich-Schwabing
  • (Director: Dr. med. M. Schmid)
1975 - 1982
Residency and Fellowships
German Heart Center, Munich (Director: Prof. Dr. med. W. Rudolph)
1982 - 1986
Assistant Professor
Department of Internal Medicine, Division of Cardiology, Medizinische Klinik Innenstadt, Ludwig-Maximilians-University (LMU), Munich
1982 - 1986
Director, Nuclear Cardiology, University of Munich
1982 - 1986
Member, Isotope and Formulatory Committee, University of Munich
1982 - 1986
Director, ST-Segment Holter Monitoring Laboratory, University of Munich
1986 PhD-equivalent Thesis, („Habilitation“)
at the Ludwig-Maximilians-University, Munich (Prof. Dr. med. E. Buchborn)
Topic: "Nitrate Tolerance: Induction, Rational Circumvention and
Consequences for a Combination Therapy"
1987 - 1989
Associate Professor
Department of Medicine, Cardiology,
University of Alabama at Birmingham (UAB), USA (Director: G.M. Pohost)
1987 - 1989
Director, Holter Laboratory and Cardiac Pharmacology Clinic, UAB, USA
1990 Attending physician, Cardiology Associates at the Red Cross Hospital, Frankfurt/Main, Germany
1990
Associate Professor, Johann Wolfgang Goethe University of Frankfurt/Main, Germany
1996
Associate Professor, Ludwig-Maximilians-University (LMU), Munich
1998 Full Professor of Medicine at the Ludwig-Maximilians-University (LMU), Munich
Today Private practice since 1991 (all insurances),
Cardiology Associates in Munich
and
Director, Heart Center at the Isar, Munich
 
Academic Teaching Practice of the Ludwig-Maximilians-University, Munich
applying the MeCuM (Medical Curriculum Munich) Medical School Concept
for advanced medical students.
MEDICAL LICENSURES and BOARD CERTIFICATIONS:
1974 ECFMG #2254209 (for USA Medical License)
1975 General Medical License (Germany)
1981 Subspecialty Board of Nuclear Cardiology
1984 Board of Internal Medicine (Germany)
1984 Board of Cardiology (Germany)
2003 Board of Endovascular Radiation Therapy (Germany)
PROFESSIONAL MEMBERSHIPS:
American College of Cardiology (ACC)
American Heart Association (AHA), Council of Clinical Cardiology, Professional Member
American Society of Nuclear Cardiology (ASNC)
Bavarian Society of Cardiologists in Private Practice (BFK), founding member
European Council of Cardiology Practice (ECCP), founding member
European Society of Cardiology (ESC)
German Society of Cardiology and Cardiovascular Research (DGK)
European Council of Cardiology Practice (ECCP)
German Society of Internal Medicine (BDI)
German Society of Interventional Cardiology (BIK), founding member
Working Group for Interventional Cardiology of the German Society of Cardiology (DGK)
Working Group for Nuclear Cardiology of the German Society of Cardiology (DGK)
Working Group for Cardio-CT of the German Society fof Cardiology (DGK)
HONORABLE MEMBERSHIPS:
FESC (Fellow of the European Society of Cardiology)
FACC (Fellow of the American College of Cardiology)
FAHA (Fellow of the American Heart Association)
CURRENT HONORABLE FUNCTIONS and ELECTED POSITIONS:
President, Bavarian Society of Cardiologists in Private Practice (BFK)
Executive Board, German Society of Interventional Cardiology (BIK)
Executive Board, Quality Control of Invasive Procedures in Bavaria (BAQ)
Appointed Expert for Disease Management Programs (DMP) for CAD in Germany
Appointed Expert for National Guidelines for Chronic CAD in Germany
Member of the Nucleus of the Working Group „Cardiac CT“ of the DGK
President, Annual Symposium of p-c-i live in Munich
Associate Director, TCT
Editorial Board, EuroIntervention Journal
Editorial Board, Clinical Research in Cardiology Journal
Editor-in-Chief of the bilingual Journal „CCN“ (Cathlab and Cardiovascular News)
PREVIOUS HONORABLE FUNCTIONS and ELECTED POSITIONS:
Chairman, PCI Guidelines of the European Society of Cardiology (ESC)
President, German Society of Cardiologists in Private Practice (BNK)
Vice President, German Society of Interventional Cardiology (BIK)
Chairman, Working Group of Interventional Cardiology (DGK)
Chairman, Working Group of Intracoronary Brachytherapy (DGK)
Member of the Committee for Practice Guidelines and Policy Conference of the ESC
Member of the Guideline Committee of the German Cardiac Society (DGK)
 
Treasurer of the Board, European Council of Cardiology Practice (ECCP)
Member of the 3rd Task Force of the ESC for the Prevention of Cardiovascular Diseases
Member of the ESC Task Force for Implementation of the Guidelines for the Management of Heart Attacks
PREVIOUS HONORABLE FUNCTIONS and ELECTED POSITIONS:
Chairman, PCI Guidelines of the European Society of Cardiology (ESC)
President, German Society of Cardiologists in Private Practice (BNK)
Vice President, German Society of Interventional Cardiology (BIK)
Chairman, Working Group of Interventional Cardiology (DGK)
Chairman, Working Group of Intracoronary Brachytherapy (DGK)
Member of the Committee for Practice Guidelines and Policy Conference of the ESC
Member of the Guideline Committee of the German Cardiac Society (DGK)
 
Treasurer of the Board, European Council of Cardiology Practice (ECCP)
Member of the 3rd Task Force of the ESC for the Prevention of Cardiovascular Diseases
Member of the ESC Task Force for Implementation of the Guidelines for the Management of Heart Attacks
EDITORIAL CONSULTANT for PEER-REVIEWED JOURNALS:
American Heart Journal
American Journal of Cardiology
American Journal of Medicine
Catheterization and Cardiovascular Intervention
Circulation
Clinical Cardiology
Clinical Research in Cardiology
Deutsche Medizinische Wochenschrift
EuroIntervention
European Heart Journal
Heart
International Journal of Cardiology
JACC
JAMA
Lancet
PARTICIPATION IN CLINICAL MULTICENTER STUDIES:
A.A.C.H.E.N. (Angiotensin-II Antagonist to reduce post Coronary stent Hyperplasia of Endothelial Neointima)
ACUITY (A randomized comparison of bivalirudin vs. heparin and GP IIb/IIIa inhibitors in patients undergoing early invasive management for NSTE-ACS)
ARTIST (Angioplasty vs. Rotablation for In-Stent restenosis)
BETA-CATH (Beta Cath System Study for brachytherapy of de-novo coronary lesions)
BRIE (Beta Radiation In Europe), Principal Investigator for Germany
CAST (Cardiac Arrythmia Supression Trial)
CHARISMA (Clopidogrel for High Atherothrombotic Risk and Ischaemic Stabilization)
CYPHER (German Registry for prospective Evaluation and Follow-up of Patients after Cypher Stent Implantation)
DaVINCI (Registry for prospective Evaluation and Follow-up of Patients after Vision Stent Implantation)
DES.DE (German Drug-Eluting Stent Registry), Member of the Steering Committee
DETECT (Diabetes Cardiovaskular Risk-Evaluation), Member of the Steering Committee
DUETT (A Novel Vascular Sealing Device for Closure of Percutaneous Arterial Access Sites), Principal Investigator
EBEAT (Electron Beam Computed Tomography assessment of coronary calcification), Member of the Safety/Endpoint Committee (SEC)
ENDEAVOR II (Randomized, controlled trial to Evaluate the AVE ABT-578 Eluting Driver Sten)
EURO HEART SURVEY (A prospective Registry Study of the European Society of Cardiology)
EUROSTAR II (European prospective study of the COSTAR Paclitaxel-Eluting Coronary Stent System as compared to the bare stent), Principal Investigator
EVIDENT (Endovascular Investigation Determining the safety of new Tacrolimus-eluting stent grafts)
EVOLVE-II (Randomized Evaluation of a Novel Bioabsorbable Polymer-Coated, Everolimus-Eluting Coronary Stent), Principal National Investigator
EXPRESS (International Registry for prospective Evaluation of patients after EXPRESS Stent Implantation), Principal Investigator
HEALING II + IIb (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth: Progenitor Endothelial Cells)
IMPULSE (Impact Upon Long lesion Stenting)
ISAR-PROJECT-2 (Clinical Evaluation of on-site coating with two Rapamycin dose regimes)
IST (Intracoronary Radiation Therapy), Principal Investigator
IT Biodegradable Study (The Biodegradable Poly-L-Lactic Acid Igaki-Tamai Coronary Stent), Principal Investigator
LUNAR ROX (Registry for prospective Evaluation of Patients after Lunar Rox Stent Implantation), Principal Investigator
LUSTY (Lunar Stent study), Principal Investigator
MASTER (The MGuard mesh-based Embolic Protection Stent for Acute ST-Elevation Reperfusion Trial), Co-Principal Investigator
MUNICH (Multislice Normal Incidence of Coronary Health), Principal Investigator
NOBORI-1 (Prospective, Randomized, Multi-Center Comparison of the Nobori and Taxus Drug Eluting Stent System), Member of the Steering Committee
NIRTOP ('Fused-Gold' vs. 'Bare' Stainless Steel NIRflex Stents), Member of the Steering Committee
NUGGET (Nir Ultimate Gold-Gilded Equivalency Trial)
OPEN II (Assessment of the STENTYS Paclitaxel-eluting selfexpanding stent in coronary bifurcation lesions)
PETN (Pentaerythrityltetranitrate Evaluation of Tolerance to Nitrates), Principal Investigator
PLATINUM PLUS (Randomized Multicenter Trial to Assess the Everolimus-Eluting Coronary Stent System), Co-Principal Investigator
RECALL (Heinz Nixdorf Recall Study), Advisory Board
REMEDEE (Randomized Study to Evaluate the Combo Abluminal Sirolimus Coated Bio-Engineered Stent)
RENO (Multicentre European Registry of intraluminal coronary Beta Brachytherapy)
RESCUT (Restenosis Cutting Balloon Evaluation)
RESOLUTE-AC (All-Comers Randomized Comparison of a Zotarolimus-Eluting Stent with an Everolimus-Eluting Stent for PCI), Co-Principal Investigator
REVEAL HPS 3 / TIMI 55 (Randomized Evaluation of Anacetrapib in pats. with established vascular disease for increasing HDL-Cholesterol) 
SAFE (A global post-market surveillance for the Dexamethason eluting Stent)
SCORE (Study to compare restenosis rate of the Quanam 7-hexanoyltaxol-eluting stent)
SEAL (Safe and Effective Arterial Closure)
START (Stents and Radiation Therapy)
TAXUS-I (Randomized, Double-Blind Trial on a Slow-Release Paclitaxel-Eluting Stent for De Novo Coronary Lesions)
TAXUS-II (Randomized Study of Slow- or Moderate-Release Polymer-Based Paclitaxel-Eluting Stents)
TAXUS-VI (Randomized, double-blind study to assess paclitaxel-eluting stents in the treatment of longer lesions)
OLYMPIA (Global TAXUS Liberté Registry)
ZOMAXX I (Randomized Evaluation of the Zomaxx ABT 578-eluting stent compared to the Taxus Express Paclitaxel-Eluting Stent)
BIBLIOGRAPHY:
Over 200 full publications in peer-reviewed journals and many book chapters, please see separate file.