Prof. Dr. med Sigmund Silber

CV of Prof. Dr. med. Sigmund Silber

Sigmund Silber, MD, FACC, FESC Professor of Medicine

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born:	11th of May, 1949 in Passau, Bavaria, Germany
Citizenship:	Germany
Family Status:	married since 1972, 2 children (Daniel born 1976 and Dalia born 1979)
PROFESSIONAL EXPERIENCE and ACADEMIC DEGREES:
1968	B.S.-equivalent (Abitur at Rupprecht-Gymnasium, Munich, Germany)
1968 - 1974	Medical School at the University of Munich (Ludwig-Maximilians-Universität, LMU)
1968 - 1974
1974	ECFMG #2254209 (for USA medical license)
1975	1970 - 1974: Research Associate Institute for Experimental Cardiovascular Pharmacology, University of Munich Thesis (MD) ,Dissertation, Institute for Experimental Cardiovascular Pharmacology, University of Munich Topic: "Effects of Aescin on the Circulation of the Cat" (with summary in English) Magna cum Laude
1974 - 1975	Internship - Stiftsklinik Augustinum Munich (Director: Prof. Dr. med. D. Michel) - II. Frauenklinik der Univ. Munich (Director: Prof. Dr. med. K. Richter) - Krankenhaus Munich- Schwabing (Director: Dr. med. M. Schmid)
1974 - 1975
1975 - 1982	Residency and Fellowships German Heart Cednter, Munich (Director: Prof. Dr. med. W. Rudolph)
1982 - 1986	Assistant Professor Department of Internal Medicine, Division of Cardiology Medizinische Klinik Innenstadt, University of Munich
1982 - 1986	Director, Nuclear Cardiology
1982 - 1986	Member, Isotope Committee
1982 - 1986	Director, ST-Segment Holter Monitoring Laboratory
1982 - 1986	Member, Formulary Committee
1986	Thesis (PhD-equivalent, Habilitation) at the Ludwig-Maximilians-Universität München (Prof. Dr. med. E. Buchborn) Topic: "Nitrate Tolerance: Induction, Rational Circumventiion and Consequences for a Combination Therapy"
1987 - 1989	Associate Professor Department of Medicine, The University of Alabama at Birmingham (UAB), USA
1987 - 1989	Director, Holter Laboratory
1987 - 1989	Director, Cardiac Pharmacology Clinic
987 - 1989	Member, Pharmacy & Therapeutics Committee
1990	Staff, attending physician Cardiology Associates at the Red Cross Hospital, Frankfurt/Main, Germany
1990	Associate Professor at the Johann Wolfgang Goethe Universität of Frankfurt/Main, Germany
1991	Private Practice Cardiology Associates in Munich and at the Dr. Müller Hospital
1996	Associate Professor at the Ludwig-Maximilians-University (LMU), Munich
1998	Professor of Medicine at the Ludwig-Maximilians-University (LMU), Munich
MEDICAL LICENSURES and BOARD CERTIFICATIONS:
1974	ECFMG #2254209 (for USA medical license)
1975	Medical License (Germany)
1975	Medical License (Germany)
1981	Subspecialty Board of Nuclear Cardiology
1984	Board of Internal Medicine (Germany)
1984	Board of Cardiology (Germany)
2003	Board of Endovascular Radiation Therapy (Brachytherapy)
PROFESSIONAL MEMBERSHIPS:
European Society of Cardiology (ESC)
European Council of Cardiology Practice (ECCP)
German Society of Cardiology and Cardiovascular Research (DGK)
Working Group for Interventional Cardiology of the German Soceity of Cardiology

Working Group for Nuclear Cardiology of the German Society of Cardiology
Worling Group for Cardio-CT of the German Society fof Cardiology
German Society of Cardiologists in Private Practice (BNK)
German Society of Internal Medicine (BDI)
Federal Association of Specialists in Private Practice (BNF)
Federal Association of Specialized Internists in Private Practice (BNFI)


American Society of Nuclear Cardiology (ASNC)
American College of Cardiology (ACC)
American Heart Association (AHA), Council of Clinical Cardiology, Professional Member

HONORABLE MEMBERSHIPS:
F.A.C.C. (Fellow of the American College of Cardiology)
F.E.S.C. (Fellow of the European Society of Cardiology)
EDITORIAL CONSULTANT: (in alphabetic order)
American Heart Journal American Journal of Cardiology American Journal of Medicine Catheterization and Cardiovascular Intervention Clinical Cardiology Circulation Deutsche Medizinische Wochenschrift Drug Safety HERZ International Journal of Cardiology JAMA Journal of the American College of Cardiology MMW - Fortschritte der Medizin Zeitschrift für Kardiologie Clinical Research in Cardiology












HONORABLE FUNCTIONS and ELECTED POSITIONS:
Chairman of the ESC Guideline Committee for Percuutaneous Interventional Cardiology (PCI)
Member of the ESC Task Force for Implementation of the Guidlines for the Management of Heart Attacks
Member of the 3rd ESC Task Force for the Prevention of Cardiovascular Diseases
Vice President of the Working Group for Interventional Cardiology of the German Society of Cardiology
President of the Working Group "Brachytherapy" of the German Society of Cardiology
Member of the Nucleus of the Working Group Cardio-CT of the Berman Society of Cardiology
Member of the Project Group "Quality Assurance" of the German Society of Cardiology (DGK)
Member of the Task Force Cardiology of the BAQ (Bavarian Working Group for Quality Assurance for in-Hospital Patients)
Scientific Board of the Working Group for Cardiovascular Prevention and Rehabilitation (LAG)
Board Member, Federal Association of Specialized Internists in Private Practice (BNFI)
Delegate of the Specialists for Disease Management Programs (DMP) for Coronary Artery Disease in Bavaria
Board Member and Treasurer of the European Council of Cardiology Practice (ECCP)
Chairman, Working Group for Interventional Cardiology of the German Society of Cardiology
reappointed as member of the guideline committee of the European Society of Cardiology (ESC)
PREVIOUS HONORABLE FUNCTIONS:
1995 - 2002	Delegate for the Journal HERZ, Internet and Speaker of the German Society of Cardiologists in Private Practice (BNK)
2000 - 2002	Member of the Committee for Practice Guidelines and Policy Conference (CPGPG) of the European Society of Cardiology (ESC) Certificate of Appreciation Letter from the ESC-President
2005 - 2007	President, German Society of Cardiologists in Private Practice (BNK)
PARTICIPATION IN QUALITY ASSURANCE PROGRAMS:








QuIK (Quality Assurance for Invasive Cardiology of the German Society of Cardiologists in Private Practice (BNK)
Quality Conferences PCI of the Social Health Care Providers in Bavaria (KVB)
BQS, Quality Assurance for in-patients
PARTICIPATION IN NATIONAL AND INTERNATIONAL MULTICENTER-STUDIES (in alphabetic order):
A.A.C.H.E.N.	Angiotensin-II Antagonist to reduce post Coronary stent Hyperplasia of Endothelial Neointima
ACUITY	A randomized comparison of bivalirudin vs. heparin and GP IIb/IIIa inhibitors in patients undergoing early invasive management for NSTE-ACS
ARTIST	Angioplasty vs. Rotablation for In-STent restenosis
BETA-CATH	Beta Cath System Study for de-novo coronary lesions
BRIE	Beta Radiation In Europe Principal Investigator for Germany
CAST	Cardiac Arrythmia Supression Trial
CHARISMA	Clopidogrel for High Atherothrombotic Risk and Ischaemic Stabilization, Management and Avoidance a placebo-controlled long-term study
CYPHER	German Registry for prospective Evaluation and Follow-up of Patients after CYPHER Stent Implantation
DaVINCI	Registry for prospective Evaluation and Follow-up of Patients after VISION Stent Implantation
DES.DE	German Drug Eluting Stent-Registry
DETECT	Diabetes Cardiovaskular Risk-Evaluation: Targets and Essential Data for Commitment of Treatment Advisory Board
EBEAT	Electron BEam computed tomography assessment of coronary calcification in high-risk patients with minimal of moderate atherosclerosis receiving intensified lipid lowering Atorvastatin Therapy Safety/Endpoint Committee (SEC)
ENDEAVOR II	A randomized, controlled trial to Evaulate the Safety and Efficacy of the MedtroNic AVE ABT-578 Eluting Driver StEnt in de-novo nAtiVe cOronary aRtery lesions
EURO HEART SURVEY	ESC- Euro Heart Survey on Coronary Revascularisation for Ischemic Heart Disease Questions Euro Heart Survey Certificate Euro Heart Survey Letter of Appreciation
EUROSTAR II	Prospective, Multi-Center, Randomized, European Study of the COSTAR Paclitaxel-Eluting Coronary Stent System in Patients with De Novo Lesions of Native Coronary Arteries
EVIDENT	EndoVascular Investigation DEtermining the safety of New Tacrolimus eluting stent grafts
EXPRESS	International Registry for prospective Evaluation of patients after EXPRESS Stent Implantation Pricipal Investigator
HEALING II	Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth: Progenitor Endothelial Cells on a Stent
IMPULSE	IMPact Upon Long lesion StEnting
ISAR-PROJECT-2	Clinical Evaluation of on-site coating with two Rapamycin dose regimes: An international, prospective, placebo-controlled, randomized study
IST	Intracoronary Radiation Therapy Pricipal Investigator
LUNAR ROX	Registry for prospective Evaluation and Follow-up of Patients after Lunar Rox Stent Implantation Pricipal Investigator
LUSTY	LUnar STent studY Pricipal Investigator
MUNICH	MUltislice Normal Incidence of Coronary Health Pricipal Investigator
NOBORI-1	A Prospective, Randomized, Multi-Center Comparison of the Nobori and Taxus Drug Eluting Stent System
NIRTOP	'Fused-Gold' vs. 'Bare' Stainless Steel NIRflex Stents of the Same Geometric Design in Diseased Native Coronary Arteries Steering Committee
NUGGET	Nir Ultimate Gold-Gilded Equivalency Trial
PETN	Pentaerythrityltetranitrat Evaluierung der Toleranzentwicklung mit Nitraten Pricipal Investigator
RECALL	Heinz Nixdorf Recall Studie Advisory Board
RENO	A multicentre European registry of intraluminal coronary beta brachytherapy
RESCUT	REStenosis CUTting balloon evaluation
SAFE	A global post-market surveillance for the Dexamet Stent (Registry of the Dexamethason eluting Stents)
SCORE	Study to COmpare REstenosis rate between queist and quadds-qp2
SEAL	Safe and Effective Arterial CLosure
START	STents And Radiation Therapy
TAXUS-I	A Randomized, Double-Blind Trial on a Slow-Release Paclitaxel-Eluting Stent for De Novo Coronary Lesions
TAXUS-II	A randomized Study to Assess the Effectiveness of Slow- and Moderate-Release Polymer-Based Paclitaxel-Eluting Stents for Coronary Artery Lesions
TAXUS-VI	A randomized, double-blind study to assess paclitaxel-eluting stents in the treatment of longer lesions
OLYMPIA	A Global TAXUS Liberté Registry
ZOMAXX I	A Randomized, Controlled Trial to Evaluate the Safety and Efficacy of the ZoMaxx Drug-Eluting Coronary Stent System Compared to the TaxusTM Express Paclitaxel-Eluting Coronary Stent in de novo Coronary Artery Lesions
TEACHING AND RESEARCH:
Teaching Courses at the Ludwig-Maximilians-University Munich according to the Concept of "problem-orientierted learning" of the Harvard Medical School Munich Model of the Harvard Medical School Academic Private Practice of the Ludwig-Maximilians-University, Munich according to the MeCuM (Medical Curriculum Munich) Medical School Concept
Students and Postgraduate Education for Medical Theses
Research Projects:
Drug- eluting Stents
Intracoronary Radiation for Therapy of in-Stent Restenosis (Brachytherapy")
Arterial Closure Devices for Immediate Hemostasis after PCI
Scoring of Calcified Coronary Plaques to identify Patients at high risk for Myocardial Infarction
Non-invasive Coronary- and Bypass-Angiography