- Brachytherapy in total occlusions. a subgroup analysis
from the reno registry, currently a database of one thousand
patients
- G. Richardt (1), D. Jain (1), V. Geist (1), F. Hartmann (1),
A. Colombo (2), D. Serruys (3), D. Baumgart (4), E. Eeckhout
(5), S. Silber (6), H.A. Katus (1)
1, University of Luebeck, Med. Clinic II, Lübeck, Germany
2, Hospital Milan, Cardiology Dept., Milan, Spain
3, Hospital of Rotterdam, Cardiology Dept., Rotterdam, Netherlands
4, University of Essen, Cardiology Dept., Essen, Germany
5, CHUV Lausanne, Cardiology Dept, Lausanne, Netherlands
6, Cardiology Clinic Dr. Müller, München, Germany
- Eur Heart J 22, Abstract suppl., 389, (2001)
|
The results of
conventional PCIs (percutaneous coronary interventions) in total
occlusions have not been salutary. We report the preliminary
results of brachytherapy in total occlusions (TO) from the RENO
registry.
Methods and Results: Seventy six patients (average age
60.46+11 years, 84% males, 32% diabetics, and 29% with unstable
angina) with 80 total occlusions (30% de novo, 3.8% restenosis,
66.3% in-stent restenosis) were registered. The procedural success
was achieved in 93.6% (47.5% received stents, and in a majority,
40mm source length with a mean dwell time of
3.47+0.8 min and 18.4+2.89 Gy, was used). The six-month follow
up (including the in-hospital events) of 48 patients, compared
with all other patients in the registry is tabulated as follows:
(table is missing). Overall there is no significant difference.
In TO, while symptomatic
improvement is seen in over 80% patients, the angiographic restenosis
is present in 29% (only half of which being total reocclusions),
far less than conventional PCI (inferred from literature).
Conclusions: The results of brachytherapy in TO are comparable
to that in a general population of patients undergoing brachytherapy,
and better than that following conventional PCI. |
